Mesa—Arizona’s third-largest city—has a pizza scene that’s as dynamic as its desert landscape.
Modern artisan spots mingle with longstanding favorites, serving up everything from Neapolitan margaritas to Arizona-inspired specialties.
Here are five fan-favorite pizzerias in 2025:
1. Vito’s Pizza & Italian Ristorante
Family-owned since the 1980s and a beloved Mesa institution, Vito’s blends New York–style tradition with Arizona creativity.
Their “Vito’s Special” (pepperoni, sausage, mushrooms, olives, onions, and bell peppers) is a best-seller, but wood-fired specialties (like the “Rustica” with prosciutto and arugula) highlight their artisanal ambition.
Hearty pastas, a full bar, and patio seating round out the experience.
2. My Pie Pizza
A build-your-own favorite, My Pie offers personal-sized, hand-tossed pizzas in minutes—with every topping imaginable.
Gluten-free, vegan, and even cauliflower crusts are available.
Signature pies include “BBQ Chicken,” “Buffalo Chicken,” and Margherita.
The fast-casual vibe and friendly service, combined with customizability, make this a staple for families and lunch breaks.
3. Nello’s Pizza
A slice of Chicago in the desert, Nello’s is legendary for deep-dish, pan-baked pies oozing with cheese and bold flavors.
Their “Nello’s Special” and stuffed spinach pie are always hits, and their thin-crust options impress those who want something lighter.
Classic booths, friendly staff, and loyal local following—Nello’s has it all.
4. La Famiglia Pizza & Pasta
La Famiglia brings authentic Italian warmth with hand-tossed pies, homemade sauce, and a big menu of pasta classics.
The “White Pie” (ricotta, mozzarella, spinach) and “Grandma Pie” (thin, square, garlicky tomato) are among Mesa’s most-craved.
The generous portions, homey atmosphere, and friendly staff win everyone over.
5. Spinato’s Pizzeria
An Arizona chain with a refined-casual approach, Spinato’s serves sweet tomato sauce and creative toppings on both classic round pies and square Sicilian slices.
Their “Super Six” (six meats and cheeses) and “Mediterranean Veggie” are house favorites, while gluten-free diners appreciate their broad menu
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