5 Best Pizza Places in Sioux Falls, South Dakota to Try

Sioux Falls has quietly built a reputation as South Dakota’s food capital, and the city’s pizza scene is one of its most satisfying surprises.

Here, classic Midwestern crowd-pleasers join inventive chef-driven spots and neighborhood institutions.

Whether you’re hunting for thick, cheesy comfort or crispy artisan slices, these are the five best places for pizza in Sioux Falls in 2025.

1. Tomacelli’s Pizza & Pasta

A true Sioux Falls institution, Tomacelli’s is consistently named the city’s top pizza shop.

Family-owned for decades, it’s beloved for its signature garlic-infused thin crust, house-made sauces, and abundant cheese and topping selections.

The “Combonation” pizza—loaded with sausage, pepperoni, beef, onions, green peppers, and black olives—remains a favorite, while the veggie and white sauce pies have earned cult status.

With a cozy, welcoming dining room and takeout that travels well, Tomacelli’s sets the bar for local comfort and flavor.

2. PizzaRev

PizzaRev brings modern, build-your-own energy to Sioux Falls, making it a huge hit for groups, picky eaters, and families.

Customize your crust (including gluten-free and cauliflower), sauce, cheese, and dozens of premium toppings for a pie baked in minutes in their high-powered oven.

Regulars rave about the creative sauces, vegan options, and the “Double Cheesy” crust.

The hip, casual setting draws college students for lunch, but it’s also great for takeout or late-night cravings.

3. Boss’ Pizza & Chicken

For late nights, sports fans, and massive portions, nothing beats Boss’.

Famous for both hearty, loaded pizzas and fried chicken (yes, really), Boss’ serves up creative specialties like the “Chicken Bacon Ranch” and “Crazy Crust” pizzas.

Open late every day, it’s a favorite for students, night-shifters, and anyone who appreciates a thick, cheesy, craveable slice.

4. Papa Woody’s Wood Fired Pizza

Located in the lively downtown area, Papa Woody’s uses a wood-fired oven to craft ultra-crispy, slightly smoky pies.

Toppings range from the classic Margherita to the locally inspired “Buffalo & Bleu” and the indulgent “Carnivore.”

Their airy crust and hint of char set these pizzas apart, while inventive weekly specials and a bustling, family-friendly atmosphere make it a go-to spot for pizza foodies.

5. Guisseppi’s Italian Restaurant

Part old-world Italian eatery, part neighborhood spot, Guisseppi’s wows with hand-tossed, thin and thick-crust pizzas.

The menu features house-made dough, rich red sauce, and both classic and gourmet toppings (try the “White Pizza” or loaded “Super Deluxe”).

Locals love the retro red-check décor, friendly service, and robust Italian menu—perfect for families or date night.