5 Best Pizza Places in Ames, Iowa to Try

Ames combines Iowa State University influence, Midwest agricultural roots, and surprising cultural depth.

Here’s where locals grab their favorite pies in 2025.

1. The Great Plains Sauce & Dough Company

This Ames institution since 1979 creates distinctive thick-crust pies on sourdough foundations that generations of Iowa State students and faculty consider essential to the Ames experience.

Their house-made sausage and locally-sourced ingredients create authentic flavors that showcase Iowa’s agricultural bounty, while the cozy space with wooden booths hasn’t changed much in decades – exactly how locals like it.

2. Vesuvius Wood-Fired Pizza (continued)

This downtown favorite fires Neapolitan-inspired pies in a beautiful imported oven that’s the centerpiece of their open kitchen.

Their naturally leavened dough develops complex flavor through extended fermentation, while seasonal ingredients from nearby farms create distinctive combinations that change with Iowa’s growing seasons.

The “Campustown” featuring sweet corn and Iowa bacon celebrates regional connections, while their craft beer selection showcases local breweries.

3. Jeff’s Pizza Shop

This campus-adjacent favorite delivers consistent quality with that perfect balance of sauce, cheese, and toppings that defines college-town comfort pizza.

Their hand-tossed pies feature generous toppings at student-friendly prices, making this a practical option for tight budgets.

Nothing fancy here – just reliable pizza that satisfies late-night cravings without complication.

4. Blaze Pizza

This modern chain’s Ames location has distinguished itself through exceptional execution and adaptation to local preferences.

Their build-your-own model allows unlimited toppings on thin, crispy crusts prepared in just 180 seconds – perfect for Iowa State students between classes.

Beyond customization, signature combinations like the “Cyclone Country” with local touches satisfy those seeking curated experiences.

5. Prairie Moon Winery & Vineyard Pizza

This unique concept combines wood-fired pizza with Iowa winemaking in a rural setting just minutes from campus.

Their outdoor pizza kitchen creates perfect crusts topped with ingredients grown on their own property and nearby farms, while dining among the vineyard rows provides a welcome escape from campus intensity.

The beautiful seasonal patio creates the ultimate Iowa summer experience, while their tasting room serves pizza year-round.